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Environmental Concerns and Birth Defects Research in China


  • Richard H. Finnell, The Texas A&M University System Health Science Center
  • Li Zhu, Peking University Health Science Center
  • Zheng Xiaoying, Peking University

    Given the sheer size of its population, the rapid pace of its industrial growth and its geographic diversity, China must grapple with the problems associated with an ever-increasing burden of environmental contaminants and some of the highest birth defects prevalence rates in the world. In response to these problems, China has developed an outstanding birth-monitoring program to ascertain reliable data on pregnancy outcomes. Furthermore, the national "one-child" policy has created enhanced pressure to minimize any adverse pregnancy outcomes. There are regions in China where the documented rate of neural tube defects such as anencephaly and spina bifida are among the highest ever reported. As is often the case where there are high rates of birth defects, there are environmental issues associated with economic development that may lie at the root of the problem. As a whole, the country is very eager to learn more about risk factors from the environment and from their own genetic background that may be contributing to the high risks for congenital defects. This is correctly seen as the first step in developing effective intervention strategies to reduce this significant societal problem. A frank discussion on how to work together to utilize existing technology and to develop novel approaches to help study these issues would be very helpful in synergizing existing research strengths and seeding new research initiatives between Texas A&M University System and investigators throughout China.
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